Objective To assess the role of the ferroptosis-associated gene GLS2 in the prognosis of pan-cancer and immunity using bioinformatics methods. Methods GLS2 expression levels in pan-cancer were profiled using publicly available databases: The Cancer Genome Atlas. GTEx. Cancer Cell Line Encyclopedia and the International Cancer Genome Consortium. https://www.roneverhart.com/2-1-2-x-1-4-x-36-Smooth-Saddle-Threshold-NGP-410-36/